Anti-ZFYVE28 Antibody [LST2/2426] - BSA and Azide free (A252957)

Mouse monoclonal [LST2/2426] antibody to ZFYVE28 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ZFYVE28 Antibody [LST2/2426] - BSA and Azide free
Description
Mouse monoclonal [LST2/2426] antibody to ZFYVE28.
Specificity
ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human ZFYVE28 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
LST2/2426
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
96 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ZFYVE28 Antibody [LST2/2426] (A249777).
Synonyms
hLst2, Lateral signaling target protein 2 homolog, LST2, LST2_HUMAN, LYST2, MGC43699, MGC61592, Zinc finger FYVE domain containing 28, Zinc finger FYVE domain-containing protein 28
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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