Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830)

Name: Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free
Brand: Antibodies.com
SKU: A323830
Price: 295.0 USD
Availability: InStock

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$295

Recombinant human monoclonal antibody to OSMR for ELISA, FACS, Functional Assay and In Vivo.

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Delivery

Freight Charges

$40 to United States

Lead Time

7-10 Business Days

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+1 (314) 370-6046

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Recombinant Antibody

Specifications

Name

Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free

Description

Recombinant human monoclonal antibody to OSMR.

Applications

ELISA, FACS, Functional Assay, In Vivo

Reactivity

Human, Cynomolgus Macaque

Host

Human

Clonality

Monoclonal

Isotype

IgG4SP - Human IgG4 with S228P mutation

Light Chains

lambda

Conjugate

Unconjugated

Purification

Protein A affinity chromatography.

Concentration

Reconstitution dependent.

Molecular Weight

This antibody has a predicted MW of 145 kDa.

Purity

> 95% (by SDS-PAGE and SEC-HPLC).

Product Form

Lyophilized

Reconstitution

Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!

Formulation

Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyms

IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, Interleukin-31 receptor subunit beta, MGC140467, MGC150626, MGC150627, MGC75127, Oncostatin M receptor, Oncostatin M specific receptor subunit beta, Oncostatin M-specific receptor, beta, Oncostatin-M-specific receptor subunit beta, OSMRB, OSMR_HUMAN

Suitable Secondaries

See all Anti-Human IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (6)

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Figure 1: SDS-PAGE - Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830)

SDS-PAGE analysis of Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.

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Figure 2: Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830)

SEC-HPLC analysis of Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830) confirms that the purity of this antibody is 96.9%.

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Figure 3: Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830)

Immobilized recombinant human OSMR protein (His tag) at 2 µg/ml is bound by Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830). EC₅₀ = 0.0024 µg/ml.

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Figure 4: Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830)

Human OSMR HEK293 cells were stained with Vixarelimab Biosimilar - Anti-OSMR Antibody - Low endotoxin, Azide free (A323830) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC₅₀ = 0.0359 µg/ml.

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