Recombinant Anti-VEGFA Antibody [VEGFA/7635R] (A315776)

Anti-VEGFA Antibody [VEGFA/7635R]

Recombinant rabbit monoclonal [VEGFA/7635R] antibody to VEGFA.

This MAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

Tumor cells in astrocytomas, breast or ovarian carcinomas.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human VEGFA protein. The exact sequence is proprietary.

Rabbit

Monoclonal

VEGFA/7635R

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

19-22 kDa (reducing) / 38 kDa-44 kDa (non-reducing)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, MGC70609, MVCD1, vascular endothelial growth factor, Vascular endothelial growth factor A, vascular endothelial growth factor A121, vascular endothelial growth factor A165, Vascular permeability factor, Vegf, VEGF A, VEGF-A, VEGF120 , VEGFA_HUMAN, VPF