Anti-VCAM1 Antibody [B-K9] (A250286)

Anti-VCAM1 Antibody [B-K9]

Mouse monoclonal [B-K9] antibody to VCAM1.

This antibody recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

Activated human umbilical vein endothelial cells (HUVEC).

Mouse

Monoclonal

B-K9

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-VCAM1 Antibody [B-K9] - BSA and Azide free (A253466).

CD106, CD106 Antigen, INCAM 100 , INCAM-100, L1CAM, MGC99561, V-CAM 1, Vascular Cell Adhesion Molecule 1, Vascular cell adhesion protein 1, VCAM 1, VCAM-1, VCAM1_HUMAN