Anti-TLR2 Antibody [11G7] (PE) (A278976)

Anti-TLR2 Antibody [11G7] (PE)

Mouse monoclonal [11G7] antibody to TLR2 (PE).

This antibody recognises the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2. Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Monoclonal

11G7

IgG1

PE

Excitation: 565nm, Emission: 578nm

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD282 antibody, clone 11G7 recognizes the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (Sandor et al. 2003). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

CD282, CD282 antigen, TIL 4, TIL4, TLR 2, TLR2_HUMAN, Toll like receptor 2, Toll like receptor 2 precursor, Toll-like receptor 2, Toll/interleukin 1 receptor like 4, Toll/interleukin 1 receptor like protein 4, Toll/interleukin receptor like protein 4, Toll/interleukin-1 receptor-like protein 4

This product is for research use only. It is not intended for diagnostic or therapeutic use.