Anti-TLR2 Antibody [11G7] (FITC) (A278975)

Anti-TLR2 Antibody [11G7] (FITC)

Mouse monoclonal [11G7] antibody to TLR2 (FITC).

This antibody recognises the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2. Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Monoclonal

11G7

IgG1

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human CD282 antibody, clone 11G7 recognizes the human Toll-like receptor 2 (TLR2), a ~90 kDa type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.Mouse anti Human CD282 antibody, clone 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (Sandor et al. 2003). Clone 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.

CD282, CD282 antigen, TIL 4, TIL4, TLR 2, TLR2_HUMAN, Toll like receptor 2, Toll like receptor 2 precursor, Toll-like receptor 2, Toll/interleukin 1 receptor like 4, Toll/interleukin 1 receptor like protein 4, Toll/interleukin receptor like protein 4, Toll/interleukin-1 receptor-like protein 4

This product is for research use only. It is not intended for diagnostic or therapeutic use.