Mouse monoclonal [TS106] antibody to Thymidylate Synthase.
Specificity
This antibody recognises thymidylate synthase, an enzyme that is essential for DNA biosynthesis and acts by converting dUMP to dTMP.Thymidylate synthase is a target for the fluoropyrimidine group of cytotoxic drugs that are used to treat solid tumours.
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Molecular Weight
Approximately 36 kDa under reduced conditions.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human thymidylate synthase antibody, clone TS106 recognizes thymidylate synthase, an enzyme that is essential for DNA biosynthesis and acts by converting dUMP to dTMP.Thymidylate synthase is a target for the fluoropyrimidine group of cytotoxic drugs that are used to treat solid tumours.