Anti-TGF alpha Antibody [SPM357] - BSA and Azide free
Description
Mouse monoclonal [SPM357] antibody to TGF alpha.
Specificity
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human testicular carcinoma using Anti-TGF alpha Antibody [SPM357].
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