Anti-TFIIB Antibody [PCRP-GTF2B-1D1] (A277638)

Mouse monoclonal [PCRP-GTF2B-1D1] antibody to TFIIB for ELISA, Flow Cytometry and IP.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-TFIIB Antibody [PCRP-GTF2B-1D1]
Description
Mouse monoclonal [PCRP-GTF2B-1D1] antibody to TFIIB.
Specificity
In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Template commitment is established by the initial binding of TFIID to the TATA element of the promotor, a step which may be facilitated by TFIIA. TFIIB then acts as the bridge between TFIID and RNA polymerase II.
Applications
ELISA, Flow Cytometry, IP
Dilutions
Flow Cytometry: 1-2 µg/million cells, IP: 1-2µg / 100-500µg proteins
Reactivity
Human
Immunogen
Recombinant full-length human TFIIB protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-GTF2B-1D1
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
34.8 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TFIIB Antibody [PCRP-GTF2B-1D1] - BSA and Azide free (A278226).
Synonyms
General transcription factor IIB, General transcription factor TFIIB, gtf2b, RNA polymerase II transcription factor IIB, S300 II, S300-II, TF IIB, TF2B, TF2B_HUMAN, Transcription initiation factor IIB
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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