Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] (A277619)

Mouse monoclonal [NR5A1/3420] antibody to Steroidogenic Factor 1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420]
Description
Mouse monoclonal [NR5A1/3420] antibody to Steroidogenic Factor 1.
Specificity
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development. SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 220-461, of human Steroidogenic Factor 1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
NR5A1/3420
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
53 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] - BSA and Azide free (A278207).
Synonyms
AD4BP, Adrenal 4 binding protein, Adrenal 4-binding protein, ELP, FTZ 1, FTZ1, FTZF 1, FTZF1, Fushi tarazu factor (Drosophila) homolog 1, Fushi tarazu factor homolog 1, hSF 1, NR5A1, Nuclear receptor AdBP4, Nuclear receptor subfamily 5 group A member 1, POF7, SF 1, SF-1, SF1, SPGF8, SRXY3, Steroid hormone receptor Ad4BP, Steroidogenic factor 1 nuclear receptor, STF 1, STF-1, STF1, STF1_HUMAN
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] (A277619)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-Steroidogenic Factor 1 Antibody [NR5A1/3420] (A277619)

Top