Anti-SPHK1 Antibody (A283037)

Anti-SPHK1 Antibody

Rabbit polyclonal antibody to SPHK1.

This antibody recognises epitopes within the N-terminal region human SphK1, also known sphingosine kinase 1. SphK1 catalyzes the phosphorylation of sphingosine 1-phosphate; an important lipid mediator with multiple functions. In light of this, SphK1 has been implicated in regulation of Ca2+ homoeostasis, inflammation, immunity and cancer growth. However, its central function is thought to be in the development of the cardiovascular and central nervous system. SphK1 has a molecular weight of ~42 kDa.

IHC-P 1: 5 - 15 µg/ml

Human

Synthetic peptide corresponding to the N-terminal domain of human SphK1, conjugated to Keyhole Limpet Haemocyanin.

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human SphK1 antibody detects epitopes within the N-terminal region human SphK1, also known sphingosine kinase 1. SphK1 catalyzes the phosphorylation of sphingosine 1-phosphate; an important lipid mediator with multiple functions. In light of this, SphK1 has been implicated in regulation of Ca2+ homoeostasis, inflammation, immunity and cancer growth. However, its central function is thought to be in the development of the cardiovascular and central nervous system. SphK1 has a molecular weight of ~42 kDa.

SK 1, SK1, Sphingosine kinase 1, SPHK, SPHK 1, SPHK1_HUMAN, SPK, SPK 1