Recombinant Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free (A253185)

Name: Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free
Brand: Antibodies.com
SKU: A253185
Price: 525.0 USD
Availability: InStock

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$525

Recombinant mouse monoclonal [rSOX2/1792] antibody to SOX2 for ELISA and IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

Contact Us

Telephone

+1 (314) 370-6046

orders@antibodies.com

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Tags:

Recombinant Antibody iPSCs Marker Neural Stem Cell Marker Neuroepithelial Marker Radial Glia Marker

Specifications

Name

Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free

Description

Recombinant mouse monoclonal [rSOX2/1792] antibody to SOX2.

Specificity

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

Applications

ELISA, IHC-P

Dilutions

IHC-P: 1-2 µg/ml

Reactivity

Human, Mouse

Immunogen

Recombinant fragment, within amino acids 176-305, of human SOX2 protein. The exact sequence is proprietary.

Host

Mouse

Clonality

Monoclonal

Clone ID

rSOX2/1792

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

34 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SOX2 Antibody [rSOX2/1792] (A250005).

Synonyms

ANOP3, cb236, Delta EF2a, lcc, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX 2, SOX2_HUMAN, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: SDS-PAGE - Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free (A253185)

SDS-PAGE analysis of Anti-SOX2 Antibody [rSOX2/1792] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 2: Immunohistochemistry - Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free (A253185)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cervix using Anti-SOX2 Antibody [rSOX2/1792].

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Figure 3: Immunohistochemistry - Anti-SOX2 Antibody [rSOX2/1792] - BSA and Azide free (A253185)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cervix using Anti-SOX2 Antibody [rSOX2/1792].

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