Anti-SIRT1 Antibody (A283427)

$420

Rabbit polyclonal antibody to SIRT1 for WB.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-SIRT1 Antibody
Description
Rabbit polyclonal antibody to SIRT1.
Specificity
This antibody recognises silent mating type information regulation 2 homolog 1 (SIRT1) also known as NAD-dependent protein deacetylase sirtuin-1 (SIRT1) and regulatory protein SIR2 homolog 1.SIRT1 is a member of the sirtuin family of deacetylases that play an important role in regulating gene expression. Due to its function in DNA repair and tumorigenesis, SIRT1 has been identified as a potential therapeutic target for cancer.
Applications
WB
Dilutions
WB: 1:400
Reactivity
Human
Immunogen
A peptide corresponding to the C-terminus of human SIRT1.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Purification
Affinity chromatography.
Concentration
200 µg/ml
Molecular Weight
Approximately 117 kDa when run under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.2% Gelatin and 0.1% Sodium Azide.
Storage
Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti SIRT1 antibody recognizes silent mating type information regulation 2 homolog 1 (SIRT1) also known as NAD-dependent protein deacetylase sirtuin-1 (SIRT1) and regulatory protein SIR2 homolog 1.SIRT1 is a member of the sirtuin family of deacetylases that play an important role in regulating gene expression (Roth and Chen 2014). Due to its function in DNA repair and tumorigenesis, SIRT1 has been identified as a potential therapeutic target for cancer (Roth and Chen 2014).
Synonyms
75SirT1, hSIR2, hSIRT1, HST2, S. cerevisiae, homolog of, NAD dependent deacetylase sirtuin 1, NAD dependent protein deacetylase sirtuin 1, NAD-dependent deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog 1, SIR1_HUMAN, SIR2, SIR2 like 1, SIR2 like protein 1, SIR2, S.cerevisiae, homolog-like 1, SIR2-like protein 1, SIR2ALPHA, SIR2L1, SIRT1_HUMAN, SirtT1 75 kDa fragment, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), Sirtuin 1, sirtuin 1 ((silent mating type information regulation 2 homolog) 1, Sirtuin type 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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