Anti-Serotonin Antibody [YC5/45] (A282023)

Anti-Serotonin Antibody [YC5/45]

Rat monoclonal [YC5/45] antibody to Serotonin.

This antibody is expected to have a broad reactivity, it has been tested to react in: Human, Rat, Goldfish, Cat, Chicken, Marine file snake, Helix aspersa, Hirudo medicinalis. This antibody recognises serotonin and does not cross react with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.

IHC-Fr, IF

Species Independent

Serotonin conjugated to Bovine Serum Albumin.

Rat

Monoclonal

YC5/45

IgG2

Unconjugated

Tissue Culture Supernatant

Liquid

Supplied in 0.05% Thiomersal.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Serotonin, also known as 5-hydroxytryptamine or 5-HT is a biochemical messenger and neurotransmitter synthesized from L-tryptophan. Serotonin has a range of functions, including regulation of gastric motility, and may be related to some psychiatric disorders including schizophrenia and depression. Serotonin is widely distributed in the central and peripheral nervous system, and also in some non-neural tissues such as platelets.Serotonin appears widely conserved and Rat anti serotonin antibody, clone YC5/45 has been used successfully to demonstrate serotonin immunoreactivity using immunohistochemistry in many diverse groups including primates (Vanoli et al. 2013), rodents (Hosoda et al. 1984), prototherian mammals, avians and reptiles (Adamson and Campbell 1988), teleosts (Takeda et al. 2014) through to invertebrates including hirudinids (Masuda-Nakagawa et al. 1990) and gastropods (Osborne and Dockray 1982).

5 hydroxytryptamine, 5HT