Anti-Semaphorin 4D Antibody [A8] (A248145)

Anti-Semaphorin 4D Antibody [A8]

Mouse monoclonal [A8] antibody to Semaphorin 4D.

This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Functional Studies, Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Monkey, Mouse

PHA stimulated human peripheral blood lymphocytes.

Mouse

Monoclonal

A8

IgG1

kappa

Unconjugated

200 µg/ml

50 kDa (monomer)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Semaphorin 4D Antibody [A8] - BSA and Azide free (A251328).

A8, BB 18, BB18, CD 100, CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, Leukocyte activation antigen CD100, M sema G, MSEMA, SEM4D_HUMAN, Sema 4d, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D, Sema H, SEMA J, Sema4d, Semacl 2, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semaphorin4D, SemaphorinJ, Semcl 2, Semcl2