MA00203 shows the following reactivities with related compounds: S-Adenosylmethionine: 100%, S-Adenosylhomocysteine: < 1%, Adenosine: < 1%, L-Methionine: < 1%, Methythioadenosine (MTA): < 1%, ADP (adenosine diphosphate): < 1%, ATP (adenosine triphosphate): < 1%.
Immunogen
S-Adenosylmethionine analog Aza-SAM conjugated to KLH.
Host
Mouse
Clonality
Monoclonal
Clone ID
118-18
Isotype
IgG2b
Conjugate
Unconjugated
Purification
Affinity chromatography
Purity
> 95%
Product Form
Liquid
Formulation
Supplied in 10mM PBS, pH 7.4, with 150mM NaCl, 0.02% Sodium Azide, and 10mg/ml BSA or supplied in 10mM PBS, pH 7.4, with 150mM NaCl, 0.02% Sodium Azide, 50% Glycerol, and 10mg/ml BSA.
Immunohistochemistry staining was performed with MA00203 with benign breast tissue adjacent to carcinoma. Brown areas indicated strong positive staining in nuclear and cytoplasmic areas.
Immunohistochemistry staining was performed with MA00203 with breast cancer tissue. Cytoplasmic and nuclear areas showed negative or much weak background staining.
FC results from normal liver cell line L02 and hepatocyte carcinoma cell line Hep G2 stained with MA00203. Average fluorescence signal in Hep G2 cells was reduced compared to that in L02 cells, indicating SAM level is reduced during carcinogenesis.
