Anti-RYBP Antibody (A283155)

Anti-RYBP Antibody

Rabbit polyclonal antibody to RYBP.

This antibody recognises human death effector domain associated factor (DEDAF), also known as RING1 and YY1-binding protein, apoptin-associating protein 1 or death effector domain-associated factor or YY1 and E4TF1-associated factor 1. DEDAF is a 228 amino acid, ~32 kDa protein that associates with DED-containing proteins but does not itself contain a DED. DEDAF interacts with the death effector domains of FADD, DEDD and the proforms of caspase-8 and caspase-10. It augments the formation of complexes between CD95, FADD and caspase-8 at the cell membrane and enhances apoptosis. The protein, identified as RING1 and YY1 binding protein (RYBP) is implicated in the regulation of transcription.

WB, IHC-P

WB: 0.5 - 1 µg/ml

Human, Mouse, Rat

A peptide corresponding to amino acids 215-228 of human DEDAF.

TPKGDMSAVNDESF

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human DEDAF antibody recognizes human death effector domain associated factor (DEDAF), also known as RING1 and YY1-binding protein, apoptin-associating protein 1 or death effector domain-associated factor or YY1 and E4TF1-associated factor 1. DEDAF is a 228 amino acid, ~32 kDa protein that associates with DED-containing proteins but does not itself contain a DED. DEDAF interacts with the death effector domains of FADD, DEDD and the proforms of caspase-8 and caspase-10. It augments the formation of complexes between CD95, FADD and caspase-8 at the cell membrane and enhances apoptosis. The protein, identified as RING1 and YY1 binding protein (RYBP) is implicated in the regulation of transcription (Sawa et al. 2002).

2410018J24Rik, AAP 1, AAP1, APAP 1, APAP-1, APAP1, Apoptin associating protein 1, Apoptin-associating protein 1, cb337, Death effector domain associated factor, Death effector domain-associated factor, Death effector domain-associated factor B, DED associated factor, DED-associated factor, DED-associated factor B, DEDAF, MGC62213, RING1 and YY1 binding protein, RING1 and YY1 binding protein a, RING1 and YY1-binding protein, RING1 and YY1-binding protein B, Ring1 interactor RYBP, rybpa, RYBP_HUMAN, wu:fi34f03, YEAF 1, YEAF1, YY1 and E4TF1 associated factor 1, YY1 and E4TF1-associated factor 1, YY1- and E4TF1/GABP-associated factor 1, zgc:153842