Recombinant Anti-RRM1 Antibody [RRM1/4372R] (A278059)

Recombinant rabbit monoclonal [RRM1/4372R] antibody to RRM1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-RRM1 Antibody [RRM1/4372R]
Description
Recombinant rabbit monoclonal [RRM1/4372R] antibody to RRM1.
Specificity
Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Synthetic peptide, around amino acids 700-800, of human RRM1 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
RRM1/4372R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
94 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-RRM1 Antibody [RRM1/4372R] - BSA and Azide free (A278647).
Synonyms
R1, Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, Ribonucleoside diphosphate reductase subunit M1, Ribonucleoside reductase, large subunit, Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large chain, Ribonucleotide reductase large subunit, Ribonucleotide reductase M1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit, Ribonucleotide reductase, M1 subunit, RIR 1, RIR1, RIR1_HUMAN, RR 1, RR1, RRM 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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