Anti-Ret Antibody [RET/2975] (A315549)

$765

Mouse monoclonal [RET/2975] antibody to Ret for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Ret Antibody [RET/2975]
Description
Mouse monoclonal [RET/2975] antibody to Ret.
Specificity
The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung s disease.
Applications
IHC-P
Positive Control
Human breast, colon or prostate carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 702-848) of human RET protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
RET/2975
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
150 kDa (precursor) / 170 kDa (Mature)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
C ret, Cadherin family member 12, Cadherin related family member 16, CDHF 12, CDHF12, CDHR16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET ELE1, Ret Proto oncogene, RET transforming sequence, RET51, RET9, RET_HUMAN, tyrosine-protein kinase receptor ret
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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