Anti-Ret Antibody [RET/2975] (A315549)

Anti-Ret Antibody [RET/2975]

Mouse monoclonal [RET/2975] antibody to Ret.

The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung s disease.

Human breast, colon or prostate carcinoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 702-848) of human RET protein. The exact sequence is proprietary.

Mouse

Monoclonal

RET/2975

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

150 kDa (precursor) / 170 kDa (Mature)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

C ret, Cadherin family member 12, Cadherin related family member 16, CDHF 12, CDHF12, CDHR16, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET ELE1, Ret Proto oncogene, RET transforming sequence, RET51, RET9, RET_HUMAN, tyrosine-protein kinase receptor ret