Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!
Formulation
Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.
Storage
Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.
SDS-PAGE analysis of Relatlimab Biosimilar - Anti-LAG-3 Antibody - Low endotoxin, Azide free (A323695) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.
SEC-HPLC analysis of Relatlimab Biosimilar - Anti-LAG-3 Antibody - Low endotoxin, Azide free (A323695) confirms that the purity of this antibody is 100%.
Human LAG3 CHO cells were stained with Relatlimab Biosimilar - Anti-LAG-3 Antibody - Low endotoxin, Azide free (A323695) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50 = 0.5464 µg/ml.
Relatlimab Biosimilar - Anti-LAG-3 Antibody - Low endotoxin, Azide free (A323695) inhibited the tumor growth of MC38 on human LAG3 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 53.8% at 10 mpk at D28.
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