A polyclonal antibody preparation contains antibodies from multiple B cell clones, each of which recognizes a unique epitope on the same target protein. This heterogeneity means that polyclonal antibodies can often improve assay sensitivity compared to using monoclonal antibodies, which can be especially useful when detecting scarce targets, or proteins that are likely to change conformation, as well as when performing techniques such as immunohistochemistry (IHC), immunoprecipitation (IP), or chromatin immunoprecipitation (ChIP), when certain epitopes may be masked by fixation, cross-linking, or the formation of protein complexes. A further advantage of being able to recognize multiple epitopes is that polyclonal antibodies may have broader application functionality than monoclonal antibodies. For example, a polyclonal antibody may be capable of detecting a native protein by immunohistochemistry (IHC) and its denatured form by western blotting (WB), while a monoclonal antibody may only work in one of these applications. Other general advantages of polyclonal antibodies include their relatively low cost and faster availability when a new target (e.g., SARS-CoV-2) is discovered. While polyclonal antibodies can be produced in several different species, goats are the preferred hosts for generating polyclonal antibodies in larger amounts. Compared to rabbits (the main species used for polyclonal antibody production), goats are estimated to produce around 7-8 times the amount of serum and 2-3 times the total concentration of IgG (typically around 20 mg/ml). Not only does this provide more antibody from the same animal, which can improve experimental consistency, but it also means that the cost per mg is usually lower. Goat polyclonal antibodies also simplify multiplexing with mouse, rat or rabbit antibodies when using indirect detection since anti-goat secondary antibodies are unlikely to cross-react with rodent or rabbit IgG. However, a limitation of using goats for polyclonal antibody production is that they should be 1-2 years old before being immunized, which equates to higher upkeep costs and requires forward planning to ensure enough animals are available to meet demand, and may be a factor in the relative popularity of chicken polyclonal antibodies and rabbit polyclonal antibodies.
Anti-Iba1 Antibody (A82670) | |
100µg/$4951 Citation | |
Description: | Goat polyclonal antibody to Iba1. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-tdTomato Antibody (A121690) | |
600µg/$55521 Citations | |
Description: | Goat polyclonal antibody to tdTomato. |
Applications: | WB, IF, IHC-P, IHC-Fr, IEM |
Reactivity: | tdTomato, mCherry, RFP |
Conjugate: | Unconjugated |
Anti-Transgelin Antibody (A83697) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Transgelin. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-GFAP Antibody (A83720) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to GFAP. |
Applications: | ELISA, WB |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-Myc Tag Antibody (A295120) | |
100µg/$465 | |
Description: | Goat polyclonal antibody to Myc Tag. |
Applications: | WB, IP, ICC, ELISA, ChIP |
Isotype: | IgG |
Conjugate: | Unconjugated |
Anti-FOXA1 Antibody (A83938) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXA1. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-NQO1 Antibody (A82457) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to NQO1. |
Applications: | ELISA, WB, IF, IHC |
Reactivity: | Human, Rat |
Conjugate: | Unconjugated |
Anti-alpha Smooth Muscle Actin Antibody (A82445) | |
100µg/$4952 Citations | |
Description: | Goat polyclonal antibody to alpha Smooth Muscle Actin. |
Applications: | ELISA, WB |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-VPS35 Antibody (A83699) | |
100µg/$4951 Citation | |
Description: | Goat polyclonal antibody to VPS35. |
Applications: | ELISA, WB, IHC, IF |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-FOXL2 Antibody (A83945) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXL2. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-RFP Antibody (A121675) | |
300µg/$555 | |
Description: | Goat polyclonal antibody to RFP. |
Applications: | WB, IF, IHC-P, IHC-Fr, IEM |
Reactivity: | Red Fluorescent Protein (dsRed), mCherry, mOrange, mPlum, mRFP, mStrawberry, tdTomato |
Conjugate: | Unconjugated |
Anti-GAPDH Antibody (A83722) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to GAPDH. |
Applications: | ELISA, WB, IF, IHC |
Reactivity: | Human, Rat |
Conjugate: | Unconjugated |
Anti-n-NOS Antibody (A83802) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to n-NOS. |
Applications: | ELISA, IHC, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-Perilipin-1 Antibody (A84328) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Perilipin-1. |
Applications: | ELISA, WB |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-FOXC1 Antibody (A83940) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXC1. |
Applications: | ELISA, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-Venus Antibody (A121679) | |
300µg/$555 | |
Description: | Goat polyclonal antibody to Venus. |
Applications: | WB, IF, IHC-P, IHC-Fr, IEM |
Reactivity: | Venus, GFP, EGFP, YFP |
Conjugate: | Unconjugated |
Anti-PARK7 Antibody (A83672) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to PARK7. |
Applications: | ELISA, WB, IF, IHC |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-NUMB Antibody (A83126) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to NUMB. |
Applications: | ELISA, IHC, IF, Flow Cytometry |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-SNAI1 Antibody (A84245) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to SNAI1. |
Applications: | ELISA, WB |
Reactivity: | Mouse, Rat |
Conjugate: | Unconjugated |
Anti-SIAH1 Antibody (A82459) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to SIAH1. |
Applications: | ELISA, WB, IF |
Reactivity: | Human, Rat |
Conjugate: | Unconjugated |
Anti-TFEB Antibody (A83834) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to TFEB. |
Applications: | ELISA, WB |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-NDRG1 Antibody (A83512) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to NDRG1. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-NeuN Antibody (A270544) | |
10µl - 100µl/$190 – $5452 Citations | |
Description: | Goat polyclonal antibody to NeuN. |
Applications: | WB, ICC/IF, IHC |
Reactivity: | Human, Rat, Mouse |
Conjugate: | Unconjugated |
Anti-FOXC2 Antibody (A83941) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXC2. |
Applications: | ELISA, WB, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-YFP Antibody (A121676) | |
300µg/$555 | |
Description: | Goat polyclonal antibody to YFP. |
Applications: | WB, IF, IHC-P, IHC-Fr, IEM |
Reactivity: | YFP, GFP, EGFP and Venus from Aequorea victoria. |
Conjugate: | Unconjugated |
Anti-NLRP3 Antibody (A82453) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to NLRP3. |
Applications: | ELISA, IF, IHC, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-mCherry Antibody (A121571) | |
600µg - 1.5mg/$555 – $740 | |
Description: | Goat polyclonal antibody to mCherry. |
Applications: | WB, IF, IHC-P, IHC-Fr, IEM |
Reactivity: | mCherry, tdTomato, Red Fluorescent Protein (dsRed) |
Conjugate: | Unconjugated |
Anti-HP1 alpha Antibody (A82447) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to HP1 alpha. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-KPNA3 Antibody (A83999) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to KPNA3. |
Applications: | ELISA, WB, IHC, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-FOXP3 Antibody (A82808) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXP3. |
Applications: | ELISA, WB, IF, Flow Cytometry, ICC, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-Pancreatic Polypeptide Antibody (A84102) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Pancreatic Polypeptide. |
Applications: | ELISA, WB, IF, IHC, Flow Cytometry |
Reactivity: | Human, Rat |
Conjugate: | Unconjugated |
Anti-Biglycan Antibody (A84269) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Biglycan. |
Applications: | ELISA, IF |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-beta Arrestin 2 Antibody (A83294) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to beta Arrestin 2. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-TRPM7 Antibody (A83778) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to TRPM7. |
Applications: | ELISA, IHC, IF |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-PCSK9 Antibody (A84073) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to PCSK9. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-ZO1 Antibody (A121581) | |
600µg/$555 | |
Description: | Goat polyclonal antibody to ZO1. |
Applications: | WB, IF, IHC-P, IHC-Fr |
Reactivity: | Human, Rat, Mouse, Canine, Monkey |
Conjugate: | Unconjugated |
Anti-POMC Antibody (A83735) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to POMC. |
Applications: | ELISA, IHC, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-Iba1 Antibody (A83214) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Iba1. |
Applications: | ELISA, Flow Cytometry, IF, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-CBR1 Antibody (A83856) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to CBR1. |
Applications: | ELISA, WB, IHC, IF |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-DCTN1/p150-glued Antibody (A83458) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to DCTN1/p150-glued. |
Applications: | ELISA, WB, IF, IHC, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-SIRT4 Antibody (A84006) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to SIRT4. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-Triosephosphate Isomerase Antibody (A83170) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to Triosephosphate Isomerase. |
Applications: | ELISA, WB, IHC, Flow Cytometry |
Reactivity: | Human, Mouse, Rat, Canine |
Conjugate: | Unconjugated |
Anti-FOXI1 Antibody (A83383) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to FOXI1. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-DDAH1 Antibody (A82817) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to DDAH1. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-PTBP1 Antibody (A83482) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to PTBP1. |
Applications: | ELISA, WB, IHC |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-PBR Antibody (A83177) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to PBR. |
Applications: | ELISA, WB, IHC, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
Anti-SOCS1 Antibody (A83759) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to SOCS1. |
Applications: | ELISA, Flow Cytometry, IF, IHC |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-ASS1 Antibody (A83511) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to ASS1. |
Applications: | ELISA, WB, IF, Flow Cytometry, IHC |
Reactivity: | Human, Mouse, Rat |
Conjugate: | Unconjugated |
Anti-IFT88 Antibody (A83301) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to IFT88. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human, Mouse |
Conjugate: | Unconjugated |
Anti-EHD2 Antibody (A83258) | |
100µg/$495 | |
Description: | Goat polyclonal antibody to EHD2. |
Applications: | ELISA, WB, IF, Flow Cytometry |
Reactivity: | Human |
Conjugate: | Unconjugated |
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