Anti-Placental Alkaline Phosphatase Antibody [ALPP/4109] - BSA and Azide free (A278206)

Anti-Placental Alkaline Phosphatase Antibody [ALPP/4109] - BSA and Azide free

Mouse monoclonal [ALPP/4109] antibody to Placental Alkaline Phosphatase.

This antibody recognizes a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human ALPP protein.

Mouse

Monoclonal

ALPP/4109

IgG2b

kappa

Unconjugated

1 mg/ml

70 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Placental Alkaline Phosphatase Antibody [ALPP/4109] (A277618).

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