Anti-PDGFR beta Antibody [PR7212] (A281593)

$340

Mouse monoclonal [PR7212] antibody to PDGFR beta for WB, IHC-P, IF, Flow Cytometry, IHC-Fr and IP.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-PDGFR beta Antibody [PR7212]
Description
Mouse monoclonal [PR7212] antibody to PDGFR beta.
Specificity
This antibody recognises the extracellular domain of the human PDGF receptor beta subunit., confirmed using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. Mouse anti Human CD140b antibody, clone PR7212 does not recognize PDGF receptor alpha. PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
Applications
WB, IHC-P, IF, Flow Cytometry, IHC-Fr, IP
Dilutions
Flow Cytometry: 25 µg/ml, IHC-P: 25 µg/ml
Reactivity
Human, Baboon, Monkey
Cross Reactivity
This antibody does not cross react with Mouse or Rat
Immunogen
Human skin fibroblast cell membrane extracts.
Host
Mouse
Clonality
Monoclonal
Clone ID
PR7212
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of ascites.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD140b antibody, clone PR7212 recognizes the extracellular domain of the human PDGF receptor beta subunit., confirmed using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB (Hart et al. 1987). Mouse anti Human CD140b antibody, clone PR7212 does not recognize PDGF receptor alpha. PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
Synonyms
Beta platelet derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD 140B, CD140 antigen-like family member B, CD140b, CD140b antigen, IBGC4, IMF1, JTK12, OTTHUMP00000160528, PDGF R beta, PDGF Receptor beta, PDGF-R-beta, PDGFR, PDGFR 1, PDGFR1, PDGFRB, PGFRB_HUMAN, Platelet derived growth factor receptor 1, Platelet derived growth factor receptor beta, Platelet derived growth factor receptor beta polypeptide
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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