Anti-PAX7 Antibody [SPM613] (A249571)

Anti-PAX7 Antibody [SPM613]

Mouse monoclonal [SPM613] antibody to PAX7.

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 301-505, of human PAX7 protein. The exact sequence is proprietary.

Mouse

Monoclonal

SPM613

IgG1

Protein A/G chromatography.

200 µg/ml

57 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PAX7 Antibody [SPM613] - BSA and Azide free (A252751).

HUP1, Paired box protein Pax-7