Recombinant Anti-PAX5 Antibody [rPAX5/4228] - BSA and Azide free (A252744)

Anti-PAX5 Antibody [rPAX5/4228] - BSA and Azide free

Recombinant mouse monoclonal [rPAX5/4228] antibody to PAX5.

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, within amino acids 235-382, of human PAX5 protein. The exact sequence is proprietary.

Mouse

Monoclonal

rPAX5/4228

IgG2a

kappa

Unconjugated

1 mg/ml

42 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-PAX5 Antibody [rPAX5/4228] (A249564).

B cell lineage specific activator, B cell lineage specific activator protein, B cell specific activator protein, B cell specific transcription factor, B-cell-specific transcription factor, BSAP, EBB-1, KLP, Paired box 5, Paired box gene 5, Paired box gene 5 (B cell lineage specific activator protein), Paired box gene 5 (B cell lineage specific activator), Paired box homeotic gene 5, Paired box protein Pax 5, Paired box protein Pax-5, Paired domain gene 5, PAX 5, PAX5_HUMAN, Transcription factor PAX 5