Recombinant Anti-PAX2 Antibody [PAX2/8671R] - BSA and Azide free (A316848)

$765

Recombinant rabbit monoclonal [PAX2/8671R] antibody to PAX2 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-PAX2 Antibody [PAX2/8671R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [PAX2/8671R] antibody to PAX2.
Specificity
Recognizes a protein of 42kDa, which is identified as PAX2. It is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Applications
IHC-P
Positive Control
NAMALWA cells. Human fetal kidney, renal cell carcinoma (RCC) or ovarian carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 223-354) of human PAX2 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
PAX2/8671R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
42 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
FSGS7, Paired box 2, Paired box gene 2, paired box homeotic gene 2, paired box protein 2, Paired box protein Pax 2, Paired box protein Pax-2, Paired box protein Pax2, PAPRS, Pax 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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