Anti-pan Cytokeratin Antibody [SPM115] (A250980)

Anti-pan Cytokeratin Antibody [SPM115]

Mouse monoclonal [SPM115] antibody to pan Cytokeratin.

This antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Monkey, Bovine, Canine, Rabbit, Mouse, Rat, Chicken, Turtle

Human epidermal keratin.

Mouse

Monoclonal

SPM115

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

56.5 kDa (CK10) / 50 kDa (CK14) / 50 kDa (CK15) / 48 kDa (CK16) / 40 kDa (CK19)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-pan Cytokeratin Antibody [SPM115] - BSA and Azide free (A254160).