Anti-pan Cytokeratin Antibody [KRT/1877R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [KRT/1877R] antibody to pan Cytokeratin.
Specificity
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
SDS-PAGE analysis of Anti-pan Cytokeratin Antibody [KRT/1877R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
Immunofluorescent analysis of methanol fixed MCF-7 cells stained with Anti-pan Cytokeratin Antibody [KRT/1877R] followed by Goat Anti-Mouse IgG (CF® 488) (Green). The nuclear counterstain is RedDot (Red).
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