Anti-p75 NGF Receptor Antibody [NGFR/4919] - BSA and Azide free (A278313)

Mouse monoclonal [NGFR/4919] antibody to p75 NGF Receptor for IF, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Lead Time
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Telephone
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Email
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Highlighted products for Anti-p75 NGF Receptor Antibody

Name
Anti-p75 NGF Receptor Antibody [NGFR/4919] - BSA and Azide free
Description
Mouse monoclonal [NGFR/4919] antibody to p75 NGF Receptor.
Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Applications
IF, WB, IHC-P
Dilutions
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
WM245 melanoma cells of human origin.
Host
Mouse
Clonality
Monoclonal
Clone ID
NGFR/4919
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
75 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-p75 NGF Receptor Antibody [NGFR/4919] (A277725).
Synonyms
CD271, CD271 antigen, Gp80 LNGFR, Gp80-LNGFR, Low affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Nerve growth factor receptor, Nerve growth factor receptor TNFR superfamily member 16, NGF receptor, Ngfr, p75 ICD, p75 Neurotrophin receptor, p75 NTR, p75(NTR), p75NTR, TNFR Superfamily Member 16, TNFRSF16, TNR16_HUMAN, Tumor necrosis factor receptor superfamily member 16
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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