Recombinant Anti-p40 Antibody [P40/4396R] - BSA and Azide free (A278671)

Name: Anti-p40 Antibody [P40/4396R] - BSA and Azide free
Brand: Antibodies.com
SKU: A278671
Price: 525.0 USD
Availability: InStock

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$525

Recombinant rabbit monoclonal [P40/4396R] antibody to p40 for ELISA, Flow Cytometry and IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

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Telephone

+1 (314) 370-6046

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Recombinant Antibody

Specifications

Name

Anti-p40 Antibody [P40/4396R] - BSA and Azide free

Description

Recombinant rabbit monoclonal [P40/4396R] antibody to p40.

Specificity

p40 antibody (antibody recognizing Np63 only) is an isoform of p63, is thought to function as a stem cell factor, responsible for maintaining cells in an uncommitted state with regenerative potential a role that may be recapitulated in tumors derived from these cells. p40 is normally expressed in the basal or progenitor cell layer of stratified epithelia (eg. squamous, urothelial, bronchial), basal cells of some glandular epithelia (eg. prostate), as well as myoepithelial cells of breast and salivary glands, trophoblasts and thymic epithelial cells. In tumor tissues, p40 expression is specific for squamous cell carcinoma. p40 is equivalent to p63 in sensitivity for lung squamous cell carcinoma, but it is markedly superior to p63 in specificity, which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. p40 appears to be a more reliable marker for squamous cell carcinoma.

Applications

ELISA, Flow Cytometry, IHC-P

Dilutions

Flow Cytometry: 1-2µg/million cells, IHC-P: 1-2 µg/ml

Reactivity

Human

Immunogen

Recombinant fragment, around amino acids 1-100, of human p40 protein. The exact sequence is proprietary.

Host

Rabbit

Clonality

Monoclonal

Clone ID

P40/4396R

Isotype

IgG

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A chromatography.

Concentration

1 mg/ml

Molecular Weight

63 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-p40 Antibody [P40/4396R] (A278083).

Synonyms

40 kDa Rab9 effector protein, 8430412M01Rik, 9530020d24rik, AV073337, bA65N13.1, C87311, DKFZp686P1077, OTTHUMP00000022126, OTTMUSP00000012898, OTTMUSP00000012899, OTTMUSP00000041318, RAB9 effector p40, Rab9 effector protein with Kelch motifs, RAB9p40, RABEK_HUMAN, RABEPK, RABEPK protein, RGD1310612, RP11 65N13.1, RP23-446N16.2

Isotype Controls

Suitable Secondaries

See all Anti-Rabbit IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: Immunohistochemistry - Anti-p40 Antibody [P40/4396R] - BSA and Azide free (A278671)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate tissue using Anti-p40 Antibody [P40/4396R].

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Figure 2: Immunohistochemistry - Anti-p40 Antibody [P40/4396R] - BSA and Azide free (A278671)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human prostate tissue using Anti-p40 Antibody [P40/4396R].

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Figure 3: Flow Cytometry - Anti-p40 Antibody [P40/4396R] - BSA and Azide free (A278671)

Flow cytometric analysis of PFA-fixed HeLa cells using Anti-p40 Antibody [P40/4396R] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).

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