Recombinant Anti-p40 Antibody [P40/4396R] (A278083)

Anti-p40 Antibody [P40/4396R]

Recombinant rabbit monoclonal [P40/4396R] antibody to p40.

p40 antibody (antibody recognizing Np63 only) is an isoform of p63, is thought to function as a stem cell factor, responsible for maintaining cells in an uncommitted state with regenerative potential a role that may be recapitulated in tumors derived from these cells. p40 is normally expressed in the basal or progenitor cell layer of stratified epithelia (eg. squamous, urothelial, bronchial), basal cells of some glandular epithelia (eg. prostate), as well as myoepithelial cells of breast and salivary glands, trophoblasts and thymic epithelial cells. In tumor tissues, p40 expression is specific for squamous cell carcinoma. p40 is equivalent to p63 in sensitivity for lung squamous cell carcinoma, but it is markedly superior to p63 in specificity, which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. p40 appears to be a more reliable marker for squamous cell carcinoma.

ELISA, Flow Cytometry, IHC-P

Flow Cytometry: 1-2µg/million cells, IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 1-100, of human p40 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

P40/4396R

IgG

Unconjugated

Protein A chromatography.

200 µg/ml

63 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-p40 Antibody [P40/4396R] - BSA and Azide free (A278671).

40 kDa Rab9 effector protein, 8430412M01Rik, 9530020d24rik, AV073337, bA65N13.1, C87311, DKFZp686P1077, OTTHUMP00000022126, OTTMUSP00000012898, OTTMUSP00000012899, OTTMUSP00000041318, RAB9 effector p40, Rab9 effector protein with Kelch motifs, RAB9p40, RABEK_HUMAN, RABEPK, RABEPK protein, RGD1310612, RP11 65N13.1, RP23-446N16.2