Anti-NCAM1 Antibody [SPM489] (A249477)

Anti-NCAM1 Antibody [SPM489]

Mouse monoclonal [SPM489] antibody to NCAM1.

This antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Membrane preparation of a small cell lung carcinoma.

Mouse

Monoclonal

SPM489

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

180 kDa / 145 kDa / 125 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NCAM1 Antibody [SPM489] - BSA and Azide free (A252657).

antigen MSK39 identified by monoclonal, antigen recognized by monoclonal, CD56, cell adhesion molecule, neural, 1, MSK 39, MSK39, N-CAM-1, NCAM, NCAM 1, NCAM C, NCAM-1, NCAM1_HUMAN, NCAMC, Neural cell adhesion molecule 1, Neural cell adhesion molecule NCAM, OTTHUMP00000235666