Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598)

Name: Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free
Brand: Antibodies.com
SKU: A323598
Price: 295.0 USD
Availability: InStock

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$295

Recombinant human monoclonal antibody to MASP2 for ELISA, FACS, Functional Assay and In Vivo.

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Delivery

Freight Charges

$40 to United States

Lead Time

7-10 Business Days

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Telephone

+1 (314) 370-6046

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Recombinant Antibody

Specifications

Name

Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free

Description

Recombinant human monoclonal antibody to MASP2.

Applications

ELISA, FACS, Functional Assay, In Vivo

Reactivity

Human, Mouse, Rat, Rhesus Macaque, Cynomolgus Macaque

Host

Human

Clonality

Monoclonal

Isotype

IgG4

Light Chains

lambda

Conjugate

Unconjugated

Purification

Protein A affinity chromatography.

Concentration

Reconstitution dependent.

Molecular Weight

This antibody has a predicted MW of 143.1 kDa.

Purity

> 95% (by SDS-PAGE and SEC-HPLC).

Product Form

Lyophilized

Reconstitution

Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!

Formulation

Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.

Storage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonyms

Mannan binding lectin serine peptidase 2, Mannan binding lectin serine protease 2, Mannose binding protein associated serine protease 2, MAP 19, MAP19, MASP 2, MBL associated plasma protein of 19 kD, MBL associated serine protease 2, Small MBL associated protein, sMAP

Suitable Secondaries

See all Anti-Human IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (5)

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Figure 1: SDS-PAGE - Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598)

SDS-PAGE analysis of Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.

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Figure 2: Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598)

SEC-HPLC analysis of Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598) confirms that the purity of this antibody is 98.94%.

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Figure 3: Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598)

Immobilized recombinant human MASP2A protein (His tag) at 2 µg/ml is bound by Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598). EC₅₀ = 0.006278 µg/ml.

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Figure 4: Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598)

C5b-C9 of the MBL pathway can be completely inhibited by Narsoplimab Biosimilar - Anti-MASP2 Antibody - Low endotoxin, Azide free (A323598) with an IC50 of 0.7337 µg/ml.

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