Anti-NADPH Oxidase 4 Antibody [NOX4/1245] (A249554)

Mouse monoclonal [NOX4/1245] antibody to NADPH Oxidase 4 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-NADPH Oxidase 4 Antibody [NOX4/1245]
Description
Mouse monoclonal [NOX4/1245] antibody to NADPH Oxidase 4.
Specificity
The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
Applications
ELISA
Dilutions
WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human NOX4 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
NOX4/1245
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
70 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NADPH Oxidase 4 Antibody [NOX4/1245] - BSA and Azide free (A252734).
Synonyms
Kidney oxidase 1, Kidney oxidase-1, Kidney superoxide producing NADPH oxidase, Kidney superoxide-producing NADPH oxidase, KOX, KOX 1, Kox-1, KOX1, NADPH, Nox4, NOX4_HUMAN, Renal NAD(P)H oxidase, Renal NAD(P)H-oxidase, RENOX
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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