Anti-MX1 Antibody [MX1/7529] - BSA and Azide free (A316732)

$765

Mouse monoclonal [MX1/7529] antibody to MX1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MX1 Antibody [MX1/7529] - BSA and Azide free
Description
Mouse monoclonal [MX1/7529] antibody to MX1.
Specificity
The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.
Applications
IHC-P
Positive Control
Human spleen, tonsil, breast cancer or colon cancer tissues.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 400-592) of human MX1 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
MX1/7529
Isotype
IgG2
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
72 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Human interferon regulated resistance GTP binding protein MXA, IFI 78, IFI 78K, IFI-78K, IFI78, IFI78K, Interferon induced GTP binding protein Mx1, Interferon induced protein p78, Interferon inducible protein p78, Interferon regulated resistance GTP binding protein, Interferon regulated resistance GTP binding protein MxA, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, MX, MX 1, MX dynamin-like GTPase 1, MX1_HUMAN, MxA, Myxoma resistance protein 1, Myxovirus (influenza virus) resistance 1 interferon inducible, Myxovirus (influenza virus) resistance 1 interferon inducible protein p78, Myxovirus (influenza) resistance 1 homolog of murine, Myxovirus resistance 1, mouse, homolog of, Myxovirus resistance protein 1, N-terminally processed
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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