Recombinant Anti-MUM1 Antibody [MUM1/8560R] - BSA and Azide free (A316728)

$765

Recombinant rabbit monoclonal [MUM1/8560R] antibody to MUM1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MUM1 Antibody [MUM1/8560R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [MUM1/8560R] antibody to MUM1.
Specificity
MUM1 is one of nuclear transcription factors necessary for development and activation of B lymphocytes. MUM1 belongs to the IRF gene family containing at least 10 widely expressed genes with similar DNA binding motif all involved in regulation of cell growth, transformation and induction of apoptosis as well as development of T-cell immune response. The synonym of MUM1 is Interferon Regulatory Factor 4 (IRF4). MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. Significant variation in positivity mainly due to chromosomal translocations involving MUM1 gene among T-cell lymphomas is observed. MUM1 is useful in a panel with other markers for subclassification of malignant lymphomas and identification of plasma cell differentiation. Particularly MUM1 may be useful for the identification of plasma cell differentiation when morphologic evidence is lacking and Ig light chains are difficult to interpret.
Applications
IHC-P
Positive Control
Human tonsil or diffuse large B-cell lymphoma (DLBCL).
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (corresponding to C-terminal) of IRF4 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
MUM1/8560R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
52 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Interferon regulatory factor 4, IRF 4, IRF-4, Irf4, IRF4_HUMAN, LSIRF, Lymphocyte specific interferon regulatory factor, Lymphocyte specific IRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM 1, NF EM5, NF-EM5, NFEM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, Transcriptional activator PIP
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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