Anti-MUC6 Antibody [SPM598] (A249443)

Anti-MUC6 Antibody [SPM598]

Mouse monoclonal [SPM598] antibody to MUC6.

The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 2-4 µg/ml

Human

A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence.

Mouse

Monoclonal

SPM598

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

252 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC6 Antibody [SPM598] - BSA and Azide free (A252623).

Gastric mucin-6, MUC-6, Mucin-6