Anti-MUC6 Antibody [MUC6/916] (A249444)

Anti-MUC6 Antibody [MUC6/916]

Mouse monoclonal [MUC6/916] antibody to MUC6.

The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

IHC-P: 2-4 µg/ml

Human

This antibody does not cross react with Rat.

Recombinant fragment covering tandem repeats of human MUC6 protein. The exact sequence is proprietary.

Mouse

Monoclonal

MUC6/916

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

252 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC6 Antibody [MUC6/916] - BSA and Azide free (A252624).

Gastric Mucin, Gastric mucin 6, Gastric mucin-6, MUC 6, MUC-6, MUC6 Fragment, MUC6 mucin, MUC6 mucin Fragment, MUC6_HUMAN, Mucin 6, Mucin 6 gastric, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6 Fragment