Anti-MUC6 Antibody [CLH5] - BSA and Azide free (A252622)

Name: Anti-MUC6 Antibody [CLH5] - BSA and Azide free
Brand: Antibodies.com
SKU: A252622
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [CLH5] antibody to MUC6 for Flow Cytometry, IF and IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

Contact Us

Telephone

+1 (314) 370-6046

orders@antibodies.com

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Specifications

Name

Anti-MUC6 Antibody [CLH5] - BSA and Azide free

Description

Mouse monoclonal [CLH5] antibody to MUC6.

Specificity

The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Applications

Flow Cytometry, IF, IHC-P

Dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 2-4 µg/ml

Reactivity

Human

Immunogen

A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence.

Host

Mouse

Clonality

Monoclonal

Clone ID

CLH5

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

252 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MUC6 Antibody [CLH5] (A249442).

Synonyms

Gastric Mucin, Gastric mucin 6, Gastric mucin-6, MUC 6, MUC-6, MUC6 Fragment, MUC6 mucin, MUC6 mucin Fragment, MUC6_HUMAN, Mucin 6, Mucin 6 gastric, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6 Fragment

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (2)

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Figure 1: Immunohistochemistry - Anti-MUC6 Antibody [CLH5] - BSA and Azide free (A252622)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human gastric carcinoma using Anti-MUC6 Antibody [CLH5].

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Figure 2: SDS-PAGE - Anti-MUC6 Antibody [CLH5] - BSA and Azide free (A252622)

SDS-PAGE analysis of Anti-MUC6 Antibody [CLH5] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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