Anti-MUC6 Antibody [CLH5] (A249442)

Name: Anti-MUC6 Antibody [CLH5]
Brand: Antibodies.com
SKU: A249442
Price: 545.0 USD
Availability: InStock

Enlarge Image

$545

Mouse monoclonal [CLH5] antibody to MUC6 for Flow Cytometry, IF and IHC-P.

100% Guarantee

Price Match Guarantee

Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Shipping Information

Freight/Packing Charges: $40

Dispatched from St. Louis, MO.

Lead Time: 5-8 business days.

Specifications

Name

Anti-MUC6 Antibody [CLH5]

Description

Mouse monoclonal [CLH5] antibody to MUC6.

Specificity

The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Applications

Flow Cytometry, IF, IHC-P

Dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 2-4 µg/ml

Reactivity

Human

Immunogen

A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence.

Host

Mouse

Clonality

Monoclonal

Clone ID

CLH5

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Molecular Weight

252 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MUC6 Antibody [CLH5] - BSA and Azide free (A252622).

Synonyms

Gastric mucin-6, MUC-6, Mucin-6

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation DataValidation Data (2)

Enlarge Image

Immunohistochemistry - Anti-MUC6 Antibody [CLH5] (A249442)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human gastric carcinoma using Anti-MUC6 Antibody [CLH5].

Enlarge Image

SDS-PAGE - Anti-MUC6 Antibody [CLH5] (A249442)

SDS-PAGE analysis of Anti-MUC6 Antibody [CLH5] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

Publishing research using Anti-MUC6 Antibody [CLH5] (A249442)? Please let us know so that we can list the citation on this page.