Anti-Mineralocorticoid Receptor Antibody [PCRP-NR3C2-1E3] - BSA and Azide free (A316702)

$765

Mouse monoclonal [PCRP-NR3C2-1E3] antibody to Mineralocorticoid Receptor for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Mineralocorticoid Receptor Antibody [PCRP-NR3C2-1E3] - BSA and Azide free
Description
Mouse monoclonal [PCRP-NR3C2-1E3] antibody to Mineralocorticoid Receptor.
Specificity
Mineralocorticoid hormones are primarily found in epithelial tissues where they function as regulators of Na+, K+ and H+ ion transport. Aldosterone is a mineralocorticoid that has been shown to regulate electrolyte excretion and intravascular volume and is therefore involved in blood pressure regulation. Mineralocorticoid receptor (MCR or MR) is a member of the steroid/thyroid/ retinoic nuclear hormone receptor superfamily that has been shown to activate gene transcription in response to aldosterone binding. Regulation of the mineralocorticoid receptors occurs through either receptor downregulation (negative autoregulation) or hormone-mediated upregulation (positive autoregulation). MCR association with HSP 90 appears to be required for hormone binding to MCR and subsequent MCR activation.
Applications
Flow Cytometry
Positive Control
HeLa cells.
Dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 601-673) of human NR3C2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-NR3C2-1E3
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
107 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Aldosterone receptor, MCR, MCR_HUMAN, MGC133092, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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