Anti-MHC Class II Antibody [M5/114] (FITC) (A85588)

Anti-MHC Class II Antibody [M5/114] (FITC)

Rat monoclonal [M5/114] antibody to MHC Class II (FITC).

This antibody recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.

Flow Cytometry: 2-3 µg/ml.

Mouse

Activated C57BL/6 mouse spleen cells.

Rat

Monoclonal

M5/114

IgG2b

This antibody is conjugated with Fluorescein Isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography; removing unconjugated antibody and free fluorochrome.

500 µg/ml

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.

Shipped at 4°C. Store in the dark at 2-8°C. Do not freeze!

D6S221E, DMA, DMB, DP beta 1, DP beta 1 chain, DP(W4) beta chain, DPB 1, DPB1, DPB1_HUMAN, DRB, H2Ea, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DM beta chain, HLA class II histocompatibility antigen, DP beta 1 chain, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA DMB, HLA DP1A, HLA DPB1, HLA SB alpha chain, HLA-A, HLA-A histocompatibility type, HLA-DP, HLA-DP histocompatibility type, beta-1 subunit, HLA-DP1B, HLA-DPB, HLA-DPB1, HLADM, HLADP1B, HLASB, HLASB histocompatibility type, Human MHC class II HLA SB alpha, LA class II histocompatibility antigen DP alpha 1 chain, Major histocompatibility complex class II, Major histocompatibility complex class II DP alpha 1, Major histocompatibility complex class II DP beta 1, Major histocompatibility complex, class I, A, MHC class II antigen DMB, MHC class II antigen DPB1, MHC class II DP3 alpha, MHC class II DPA1, MHC class II HLA-DP-beta-1, MHC DPB1, MHC HLA DPB1, PLT1, Primed lymphocyte test 1, RING6, RING7

This product is for research use only. It is not intended for diagnostic or therapeutic use.