Anti-Metapneumovirus Antibody [HMPV57] (A280640)

$480

Mouse monoclonal [HMPV57] antibody to Metapneumovirus for IF.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Metapneumovirus Antibody [HMPV57]
Description
Mouse monoclonal [HMPV57] antibody to Metapneumovirus.
Specificity
This antibody recognises human metapneumovirus (hMPV), a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness, while lower respiratory tract infection can cause fever, cough, pneumonia, bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young, the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection. Phylogenetic analysis has shown two major genotypes, A and B, each containing two sub-divisions, suggesting that four distinct lineages circulate in the population with different lineages predominating in different years.recognises all sub-types (A1, A2, B1 and B2) of hMPV and may be used in conjunction with clones HMPV123, HMPV33 and HMPV24 to detect all strains of hMPV. Mouse anti Metapneumovirus antibody, clone HMPV57 does not cross-react with cell cultures infected with hRSV, influenzaviruses A and B, adenovirus, parainfluenza viruses 1, 2, 3 and 4b, mumps virus, measles virus, varicella-zoster virus, herpes simplex virus types 1 and 2, human cytomegalovirus, human herpesvirus type 6, ECHOvirus 19, Coxsachievirus B4, poliovirus types 1-3, HHV6 or uninfected HeLa, MA104, 3MK, LLC-MK, HEp2, MRC-5 and HSB-2 cells. It also does not react with sputum bacteria.
Applications
IF
Dilutions
IF: 1:80 - 1:160
Reactivity
Viral
Immunogen
Sub-type A hMPV virus isolate NCL03-4/174.
Host
Mouse
Clonality
Monoclonal
Clone ID
HMPV57
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Metapneumovirus antibody, clone HMPV57 recognizes human metapneumovirus (hMPV), a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness, while lower respiratory tract infection can cause fever, cough, pneumonia, bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young, the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection. Phylogenetic analysis has shown two major genotypes, A and B, each containing two sub-divisions, suggesting that four distinct lineages circulate in the population with different lineages predominating in different years.Mouse anti Metapneumovirus antibody, clone HMPV57 recognizes all sub-types (A1, A2, B1 and B2) of hMPV and may be used in conjunction with clones HMPV123, HMPV33 and HMPV24 to detect all strains of hMPV. Mouse anti Metapneumovirus antibody, clone HMPV57 does not cross-react with cell cultures infected with hRSV, influenzaviruses A and B, adenovirus, parainfluenza viruses 1, 2, 3 and 4b, mumps virus, measles virus, varicella-zoster virus, herpes simplex virus types 1 and 2, human cytomegalovirus, human herpesvirus type 6, ECHOvirus 19, Coxsachievirus B4, poliovirus types 1-3, HHV6 or uninfected HeLa, MA104, 3MK, LLC-MK, HEp2, MRC-5 and HSB-2 cells. It also does not react with sputum bacteria.
Synonyms
hMPV
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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