Anti-MEF2D Antibody [PCRP-MEF2D-3A4] (A277705)

Mouse monoclonal [PCRP-MEF2D-3A4] antibody to MEF2D for IP, Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MEF2D Antibody [PCRP-MEF2D-3A4]
Description
Mouse monoclonal [PCRP-MEF2D-3A4] antibody to MEF2D.
Specificity
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
Applications
IP, Flow Cytometry, IF, IHC-P
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human MEF2D protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-MEF2D-3A4
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
55.94 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MEF2D Antibody [PCRP-MEF2D-3A4] - BSA and Azide free (A278293).
Synonyms
DKFZp686I1536, MADS box transcription factor 2 polypeptide D, MEF2D_HUMAN, Myocyte enhancer factor 2D, Myocyte specific enhancer factor 2, polypeptide D, Myocyte specific enhancer factor 2D, Myocyte-specific enhancer factor 2D
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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