Anti-MCM6 Antibody [MCM6/2999] - BSA and Azide free (A252478)

Mouse monoclonal [MCM6/2999] antibody to MCM6 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MCM6 Antibody [MCM6/2999] - BSA and Azide free
Description
Mouse monoclonal [MCM6/2999] antibody to MCM6.
Specificity
The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 228-368, of human MCM6 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
MCM6/2999
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
105 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MCM6 Antibody [MCM6/2999] (A249298).
Synonyms
DNA replication licensing factor MCM6, MCG40308, MCM6 minichromosome maintenance deficient 6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6_HUMAN, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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