Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free (A278291)

Name: Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free
Brand: Antibodies.com
SKU: A278291
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [MCM2/3678] antibody to MCM2 for IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

Contact Us

Telephone

+1 (314) 370-6046

orders@antibodies.com

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Specifications

Name

Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free

Description

Mouse monoclonal [MCM2/3678] antibody to MCM2.

Specificity

The specificity of this monoclonal antibody to its intended target was validated by HuProt^TM Array, containing more than 19,000 full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

Applications

IHC-P

Dilutions

IHC-P: 1-2 µg/ml

Reactivity

Human

Immunogen

Recombinant fragment, around amino acids 650-750, of human MCM2 protein. The exact sequence is proprietary.

Host

Mouse

Clonality

Monoclonal

Clone ID

MCM2/3678

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Molecular Weight

102 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MCM2 Antibody [MCM2/3678] (A277703).

Synonyms

BM28, CCNL 1, CCNL1, CDC like 1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2_HUMAN, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (3)

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Figure 1: Immunohistochemistry - Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free (A278291)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue using Anti-MCM2 Antibody [MCM2/3678]. Inset: PBS instead of the primary antibody. Secondary antibody negative control.

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Figure 2: Immunohistochemistry - Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free (A278291)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon carcinoma tissue using Anti-MCM2 Antibody [MCM2/3678].

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Figure 3: SDS-PAGE - Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free (A278291)

SDS-PAGE analysis of Anti-MCM2 Antibody [MCM2/3678] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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