Anti-Mast Cell Tryptase Antibody [AA1] (A279617)

Anti-Mast Cell Tryptase Antibody [AA1]

Mouse monoclonal [AA1] antibody to Mast Cell Tryptase.

This antibody recognises human mast cell tryptase, both alpha and beta isoforms. Mouse anti Mast cell tryptase, clone AA1 is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology. Tryptases are the products of a number of genes and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction.

WB, IHC-P, IHC-Fr, ELISA, IF

IHC-P 1: 1:10,000

Human, Dog, Monkey, Cat, Rat

Human mast cell tryptase purified from human lung tissue.

Mouse

Monoclonal

AA1

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human mast cell tryptase, clone AA1 recognizes human mast cell tryptase, both alpha and beta isoforms. Mouse anti Mast cell tryptase, clone AA1 is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology (Walls et al. 1990).Tryptases are the products of a number of genes and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction (Zhang and Timmerman 1997).

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