Anti-Maspin Antibody [SERPINB5/4975] (A277745)

Mouse monoclonal [SERPINB5/4975] antibody to Maspin for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Maspin Antibody [SERPINB5/4975]
Description
Mouse monoclonal [SERPINB5/4975] antibody to Maspin.
Specificity
Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit Chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.
Applications
WB, IHC-P
Dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 1-200, of human Maspin protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
SERPINB5/4975
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
42 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Maspin Antibody [SERPINB5/4975] - BSA and Azide free (A278333).
Synonyms
Ovalbumin, Peptidase inhibitor 5, PI-5, PI5, Protease inhibitor 5, protease inhibitor 5 (maspin), Serine (or cysteine) peptidase inhibitor, clade B, member 5, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5, Serpin B5, serpin family B member 5, Serpin peptidase inhibitor, Serpin peptidase inhibitor, clade B (ovalbumin), member 5, Serpinb5, SPB5_HUMAN, Spi5, Spi7
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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