Anti-Macrophage Inflammatory Protein 3 alpha Antibody - BSA and Azide free (A283932)

$645

Rabbit polyclonal antibody to Macrophage Inflammatory Protein 3 alpha for WB, ELISA, IHC-P and Functional Assays.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Macrophage Inflammatory Protein 3 alpha Antibody - BSA and Azide free
Description
Rabbit polyclonal antibody to Macrophage Inflammatory Protein 3 alpha.
Specificity
This antibody recognises human MIP-3 alpha, (Macrophage Inflammatory Protein 3 alpha), otherwise known as CCL20, a 70 amino acid CC chemokine predominantly expressed by the liver, lymph nodes, appendix, spleen and pancreas and also by the thymus, small intestine, foetal lungs and PBLs.MIP-3 alpha acts as a chemoattractant for memory T lymphocytes, immature dendritic cells and B lymphocytes, being the only CC chemokine known to bind to the G-protein linked 7-transmembrane receptor CCR6. Further properties of MIP-3 alpha include antimicrobial activity, inhibition of the in vitro proliferation of bone marrow immature myeloid progenitors and the stimulation of the growth and migration of pancreatic carcinoma cells.
Applications
WB, ELISA, IHC-P, Functional Assays
Dilutions
ELISA: 0.5 µg/ml, Functional Assays: 15.0 - 18.0 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant human MIP-3 alpha.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human MIP-3 alpha antibody recognizes human MIP-3 alpha, (Macrophage Inflammatory Protein 3 alpha), otherwise known as CCL20, a 70 amino acid CC chemokine predominantly expressed by the liver, lymph nodes, appendix, spleen and pancreas and also by the thymus, small intestine, foetal lungs and PBLs.MIP-3 alpha acts as a chemoattractant for memory T lymphocytes, immature dendritic cells and B lymphocytes, being the only CC chemokine known to bind to the G-protein linked 7-transmembrane receptor CCR6. Further properties of MIP-3 alpha include antimicrobial activity, inhibition of the in vitro proliferation of bone marrow immature myeloid progenitors and the stimulation of the growth and migration of pancreatic carcinoma cells.
Synonyms
Beta-chemokine exodus-1, C C motif chemokine ligand 20, C-C motif chemokine 20, CC chemokine LARC, Ccl20, CCL20(2-70), CCL20_HUMAN, Chemokine (C C motif) ligand 20, Chemokine CC motif ligand 20, CKb4, Exodus, Exodus 1, LARC, Liver and activation-regulated chemokine, MIP 3 alpha, MIP 3A, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, Small inducible cytokine A20 , Small inducible cytokine subfamily A (Cys Cys) member 20, Small-inducible cytokine A20, ST38
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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