Anti-Luteinizing Hormone Antibody [LHCGR/1417] (A249232)

Mouse monoclonal [LHCGR/1417] antibody to Luteinizing Hormone for ELISA, Flow Cytometry and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Luteinizing Hormone Antibody [LHCGR/1417]
Description
Mouse monoclonal [LHCGR/1417] antibody to Luteinizing Hormone.
Specificity
This antibody recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Applications
ELISA, Flow Cytometry, WB
Dilutions
Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 70-410, of human LHCGR protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
LHCGR/1417
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
78-85 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Luteinizing Hormone Antibody [LHCGR/1417] - BSA and Azide free (A252412).
Synonyms
CGB4, HH23, hLHB, Interstitial cell stimulating hormone beta chain, Leutropin, LH B, LH-B, LHB, LSH B, LSH beta, LSH-B, LSH-beta, LSHB_HUMAN, Luteinizing hormone beta, Luteinizing hormone beta subunit, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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